The K-chains of the Immunoglobulin from a Continuous Culture of Human Lymphocytes (daudi) Have an Unusual Molecular Size
نویسنده
چکیده
Membrane-associated immunoglobulin (M-Ig) was isolated from Daudi cells which had been radioiodinated using lactoperoxidase. This M-Ig was found to have a molecular size on SDS-PAGE of 330,000 daltons. The component protein chains (micro and K) have molecular sizes of 75,000 and 33,000 daltons, respectively. Further studies showed that [(3)H]galactose can be incorporated into K-chains, but that extra protein and not carbohydrate was responsible for the increased molecular size of this molecule.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 139 شماره
صفحات -
تاریخ انتشار 1974